Pleomorphic lipoma

Pleomorphic lipoma is a rare subtype of lipoma, a benign tumor that originates from adipose tissue. It is characterized by its pleomorphic and spindle cell components, which are unique to this type of lipoma. Pleomorphic lipomas are most commonly found in the subcutaneous tissue of the neck, back, and shoulders of elderly males.

Clinical Presentation

Patients with pleomorphic lipoma typically present with a slow-growing, painless mass. The mass is often located in the subcutaneous tissue of the neck, back, or shoulders. The size of the tumor can vary, but it is usually between 2 and 10 cm in diameter.

Pathology

Pleomorphic lipoma is characterized by its unique histological features. The tumor is composed of mature adipocytes, spindle cells, and pleomorphic cells. The spindle cells are often arranged in a "swirling" pattern, and the pleomorphic cells can have multiple nuclei.

Diagnosis

The diagnosis of pleomorphic lipoma is typically made based on the clinical presentation and histological findings. Imaging studies, such as ultrasound or MRI, may be used to evaluate the size and location of the tumor. A biopsy of the tumor may also be performed to confirm the diagnosis.

Treatment

The primary treatment for pleomorphic lipoma is surgical excision. This is usually curative, as the tumor is benign and does not typically recur after removal. In some cases, radiation therapy may be used if the tumor cannot be completely removed.

Prognosis

The prognosis for patients with pleomorphic lipoma is generally excellent. The tumor is benign and does not typically metastasize or recur after removal. However, regular follow-up is recommended to monitor for any potential recurrence.

See Also

• Lipoma
• Adipose tissue
• Tumor
• Biopsy
• Radiation therapy

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