Precursor B-lymphoblastic leukemia
Precursor B-lymphoblastic leukemia (also known as B-ALL) is a type of cancer that originates in the lymphatic system, specifically in the B cells. It is a subtype of acute lymphoblastic leukemia (ALL), which is the most common type of cancer in children. However, B-ALL can also occur in adults.
Symptoms[edit | edit source]
The symptoms of B-ALL can vary, but they often include fatigue, fever, bruising or bleeding, bone pain, and lymphadenopathy (swollen lymph nodes). Other symptoms may include anemia, infection due to a weakened immune system, and weight loss.
Causes[edit | edit source]
The exact cause of B-ALL is unknown, but it is thought to involve a combination of genetic and environmental factors. Some studies have suggested that exposure to certain chemicals or radiation may increase the risk of developing B-ALL.
Diagnosis[edit | edit source]
Diagnosis of B-ALL typically involves a bone marrow biopsy, in which a small sample of bone marrow is removed and examined under a microscope. Other tests may include blood tests, imaging tests, and lumbar puncture.
Treatment[edit | edit source]
Treatment for B-ALL usually involves chemotherapy, which is often successful in children but less so in adults. Other treatment options may include radiation therapy, stem cell transplant, and targeted therapy.
Prognosis[edit | edit source]
The prognosis for B-ALL varies depending on a number of factors, including the patient's age, overall health, and the specific characteristics of the leukemia. However, with treatment, many people with B-ALL are able to achieve remission.
See also[edit | edit source]
Precursor B-lymphoblastic leukemia Resources | |
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Contributors: Prab R. Tumpati, MD