Primary pulmonary histoplasmosis

Primary Pulmonary Histoplasmosis is a type of lung disease caused by the fungus Histoplasma capsulatum. This disease is most commonly found in the Midwestern United States and parts of Central America and Africa.

Etiology

Histoplasma capsulatum is a dimorphic fungus that can survive in the environment as a mold and in the human body as a yeast. The fungus is found in soil and material contaminated with bird or bat droppings. People get infected by inhaling the fungal spores.

Clinical Presentation

Primary pulmonary histoplasmosis often presents with flu-like symptoms such as fever, cough, and fatigue. In severe cases, it can cause a pneumonia-like illness with shortness of breath and chest pain. Some people may also develop rashes or joint pain.

Diagnosis

Diagnosis of primary pulmonary histoplasmosis is often made by identifying Histoplasma capsulatum in a tissue biopsy, sputum sample, or blood culture. Other diagnostic tests include serology and antigen detection tests.

Treatment

Most people with primary pulmonary histoplasmosis do not require treatment as the infection often resolves on its own. However, in severe cases or in people with weakened immune systems, antifungal medications such as itraconazole or amphotericin B may be used.

Prevention

Prevention of primary pulmonary histoplasmosis involves avoiding exposure to environments where Histoplasma capsulatum is likely to be found, particularly in areas with bird or bat droppings.

See Also

• Histoplasmosis
• Pulmonary disease
• Fungal infection