Pseudogout

Pseudogout is a form of arthritis that is characterized by sudden, painful swelling in one or more joints. These attacks can last for days or weeks. The term "pseudogout" was coined for the condition's similarity to gout, but the two diseases have distinct underlying causes and treatments.

Causes

Pseudogout is caused by the accumulation of calcium pyrophosphate dihydrate (CPPD) crystals in the joints. This is due to a variety of factors, including aging, genetic predisposition, and excessive calcium or iron in the blood. Certain medical conditions, such as hyperparathyroidism, hemochromatosis, and hypomagnesemia, can also increase the risk of developing pseudogout.

Symptoms

The symptoms of pseudogout are similar to those of gout and can include severe pain, redness, warmth, and swelling in the affected joints. The knee is the most commonly affected joint, but pseudogout can also affect the wrists, shoulders, ankles, elbows, and hands.

Diagnosis

Diagnosis of pseudogout is typically made through a combination of physical examination, medical history, and laboratory tests. The definitive diagnosis is made by identifying CPPD crystals in the synovial fluid of the affected joint.

Treatment

Treatment for pseudogout aims to manage symptoms and prevent future attacks. This can include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or colchicine. In severe cases, joint aspiration or surgery may be necessary.

See also

• Gout
• Arthritis
• Calcium pyrophosphate dihydrate crystal deposition disease

Pseudogout Resources
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