Ruthenium red

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Ruthenium red is an inorganic compound that is used in microscopy as a stain for certain cell components. It is a complex of ruthenium with ammonia and chloride ions.

Chemistry[edit | edit source]

Ruthenium red is a complex of ruthenium, ammonia, and chloride. The ruthenium atoms are in the +3 oxidation state. The compound is a dark red solid that is soluble in water. It has a complex structure in which each ruthenium atom is surrounded by six ammonia ligands and two chloride ligands.

Uses[edit | edit source]

Ruthenium red is used in microscopy as a stain for certain cell components. It binds to pectic acid and acidic proteins, making them visible under the microscope. It is also used in the study of the structure and function of the mitochondria, as it can inhibit the transport of calcium ions across the mitochondrial membrane.

Safety[edit | edit source]

Ruthenium red is considered to be moderately toxic. It can cause irritation to the skin and eyes, and if ingested or inhaled, it can cause harm to the respiratory and digestive systems.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD