Small lymphocytic lymphoma

From WikiMD's Wellness Encyclopedia

Small Lymphocytic Lymphoma (SLL) is a type of non-Hodgkin lymphoma characterized by the presence of small lymphocytes in the lymph nodes. It is closely related to chronic lymphocytic leukemia (CLL), and the two conditions have similar treatments and prognosis.

Symptoms and Signs[edit | edit source]

Patients with SLL may present with lymphadenopathy, hepatomegaly, splenomegaly, and B symptoms such as fever, night sweats, and weight loss. However, many patients are asymptomatic at the time of diagnosis.

Diagnosis[edit | edit source]

The diagnosis of SLL is based on the histological examination of a lymph node biopsy. The lymph nodes show a diffuse infiltration of small lymphocytes. Immunohistochemistry studies are also performed to confirm the diagnosis.

Treatment[edit | edit source]

The treatment of SLL is similar to that of CLL. It may include chemotherapy, immunotherapy, and targeted therapies. The choice of treatment depends on the stage of the disease and the patient's overall health.

Prognosis[edit | edit source]

The prognosis of SLL is variable. Some patients have a slow-growing disease that does not require treatment for many years, while others have a more aggressive disease that requires immediate treatment.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD