Small lymphocytic lymphoma

Small Lymphocytic Lymphoma (SLL) is a type of non-Hodgkin lymphoma characterized by the presence of small lymphocytes in the lymph nodes. It is closely related to chronic lymphocytic leukemia (CLL), and the two conditions have similar treatments and prognosis.

Symptoms and Signs

Patients with SLL may present with lymphadenopathy, hepatomegaly, splenomegaly, and B symptoms such as fever, night sweats, and weight loss. However, many patients are asymptomatic at the time of diagnosis.

Diagnosis

The diagnosis of SLL is based on the histological examination of a lymph node biopsy. The lymph nodes show a diffuse infiltration of small lymphocytes. Immunohistochemistry studies are also performed to confirm the diagnosis.

Treatment

The treatment of SLL is similar to that of CLL. It may include chemotherapy, immunotherapy, and targeted therapies. The choice of treatment depends on the stage of the disease and the patient's overall health.

Prognosis

The prognosis of SLL is variable. Some patients have a slow-growing disease that does not require treatment for many years, while others have a more aggressive disease that requires immediate treatment.

See Also

• Non-Hodgkin lymphoma
• Chronic lymphocytic leukemia
• Lymphadenopathy
• Hepatomegaly
• Splenomegaly

References

Small lymphocytic lymphoma Resources
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