Superior longitudinal fasciculus

Superior Longitudinal Fasciculus

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The Superior Longitudinal Fasciculus highlighted in an anatomical diagram.

The Superior Longitudinal Fasciculus (SLF) is a major white matter tract in the human brain that connects the frontal lobe and the parietal lobe. It is one of the most significant components of the dorsal stream of the visual system, playing a crucial role in spatial awareness and the coordination of movements.

Anatomy

The Superior Longitudinal Fasciculus is a bundle of axons that runs longitudinally along the lateral aspect of the cerebral hemisphere. It is divided into three parts: SLF I, SLF II, and SLF III. SLF I connects the superior parietal lobule with the superior and medial parts of the frontal lobe. SLF II connects the inferior parietal lobule with the frontal lobe, while SLF III links the supramarginal gyrus with the precentral gyrus.

Function

The SLF is involved in a variety of cognitive functions, including attention, working memory, and language processing. It is also crucial for the integration of sensory and motor information, enabling the brain to coordinate complex actions.

Clinical Significance

Damage to the Superior Longitudinal Fasciculus can result in a range of neurological disorders, including aphasia, apraxia, and hemispatial neglect. It has also been implicated in conditions such as schizophrenia and autism, with research suggesting that alterations in the structure or function of the SLF may contribute to the cognitive and behavioral symptoms associated with these disorders.

See Also

• Arcuate fasciculus
• Inferior longitudinal fasciculus
• Uncinate fasciculus