Syringocystadenoma papilliferum

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Syringocystadenoma papilliferum is a rare benign skin tumor that typically arises from apocrine glands. It is often present at birth or develops during childhood and is commonly found on the scalp and face. The lesion is characterized by its distinctive appearance and histological features.

Presentation

Syringocystadenoma papilliferum usually presents as a solitary, verrucous (wart-like) or papillomatous (nipple-like) lesion. It can vary in size and may grow slowly over time. The surface of the lesion is often covered with a crust or may be ulcerated. The color can range from pink to brown.

Histopathology

Histologically, syringocystadenoma papilliferum is characterized by the presence of papillary projections lined by epithelial cells and an underlying stroma containing numerous plasma cells. The lesion shows both cystic and adenomatous components, with the cystic spaces often filled with eosinophilic material.

Diagnosis

The diagnosis of syringocystadenoma papilliferum is primarily based on its clinical appearance and histopathological examination. A biopsy is usually performed to confirm the diagnosis and to rule out other conditions.

Treatment

Treatment options for syringocystadenoma papilliferum include surgical excision, which is often curative. In some cases, laser therapy or cryotherapy may be used. Regular follow-up is recommended to monitor for any changes in the lesion.

Prognosis

The prognosis for syringocystadenoma papilliferum is generally excellent, as it is a benign tumor with a low risk of malignant transformation. However, complete surgical removal is advised to prevent recurrence.

See also

• Skin tumor
• Apocrine gland
• Histopathology
• Benign tumor