Syringocystadenoma papilliferum

Syringocystadenoma papilliferum is a rare benign adenoma that originates from the apocrine sweat gland. It is often associated with nevus sebaceous and is usually present at birth or develops in early childhood.

Clinical Presentation

Syringocystadenoma papilliferum typically presents as a solitary, slow-growing, moist, and verrucous nodule or plaque. It is most commonly found on the scalp or face, but can occur anywhere on the body. The lesion may become inflamed and ulcerate, and can produce a clear or bloody discharge.

Pathology

Histologically, syringocystadenoma papilliferum is characterized by papillary projections into cystic spaces. The projections are lined by two layers of cells: an inner layer of columnar cells with decapitation secretion, and an outer layer of myoepithelial cells. The stroma is often infiltrated with plasma cells.

Treatment

The treatment of choice for syringocystadenoma papilliferum is complete surgical excision. This is due to the risk of malignant transformation, which has been reported in a small number of cases.

See Also

• Adenoma
• Apocrine sweat gland
• Nevus sebaceous

References

Syringocystadenoma papilliferum Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski