T-cell prolymphocytic leukemia

From WikiMD's Wellness Encyclopedia

T-cell prolymphocytic leukemia (T-PLL) is a rare and aggressive type of leukemia that affects the T cells, a type of white blood cell that plays a crucial role in the immune system. It is characterized by the overproduction of immature T cells, known as prolymphocytes, in the bloodstream.

Symptoms[edit | edit source]

The symptoms of T-PLL can vary, but often include fatigue, fever, night sweats, and unexplained weight loss. Other symptoms may include swollen lymph nodes, an enlarged spleen, and skin rashes.

Causes[edit | edit source]

The exact cause of T-PLL is unknown, but it is believed to be related to genetic mutations. Some studies have suggested a link between T-PLL and exposure to certain chemicals or radiation, but more research is needed to confirm these findings.

Diagnosis[edit | edit source]

T-PLL is typically diagnosed through a combination of blood tests, bone marrow biopsy, and genetic testing. The presence of an unusually high number of prolymphocytes in the blood or bone marrow is a key indicator of the disease.

Treatment[edit | edit source]

Treatment for T-PLL typically involves chemotherapy, immunotherapy, or a combination of both. In some cases, a stem cell transplant may be considered.

Prognosis[edit | edit source]

The prognosis for T-PLL is generally poor, with a median survival time of less than two years. However, some patients may respond well to treatment and achieve long-term remission.

See also[edit | edit source]

NIH genetic and rare disease info[edit source]

T-cell prolymphocytic leukemia is a rare disease.



T-cell prolymphocytic leukemia Resources
PubMed
Wikipedia
Medicine-stub.png
This article is a stub related to medicine. You can help WikiMD by expanding it!
WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD