T-cell prolymphocytic leukemia
T-cell prolymphocytic leukemia (T-PLL) is a rare and aggressive type of leukemia that affects the T cells, a type of white blood cell that plays a crucial role in the immune system. It is characterized by the overproduction of immature T cells, known as prolymphocytes, in the bloodstream.
Symptoms[edit | edit source]
The symptoms of T-PLL can vary, but often include fatigue, fever, night sweats, and unexplained weight loss. Other symptoms may include swollen lymph nodes, an enlarged spleen, and skin rashes.
Causes[edit | edit source]
The exact cause of T-PLL is unknown, but it is believed to be related to genetic mutations. Some studies have suggested a link between T-PLL and exposure to certain chemicals or radiation, but more research is needed to confirm these findings.
Diagnosis[edit | edit source]
T-PLL is typically diagnosed through a combination of blood tests, bone marrow biopsy, and genetic testing. The presence of an unusually high number of prolymphocytes in the blood or bone marrow is a key indicator of the disease.
Treatment[edit | edit source]
Treatment for T-PLL typically involves chemotherapy, immunotherapy, or a combination of both. In some cases, a stem cell transplant may be considered.
Prognosis[edit | edit source]
The prognosis for T-PLL is generally poor, with a median survival time of less than two years. However, some patients may respond well to treatment and achieve long-term remission.
See also[edit | edit source]
NIH genetic and rare disease info[edit source]
T-cell prolymphocytic leukemia is a rare disease.
T-cell prolymphocytic leukemia Resources | ||
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