Testosterone butyrate
Overview[edit | edit source]
Testosterone butyrate is a synthetic androgen and anabolic steroid (AAS) that is a derivative of testosterone. It is an ester of testosterone, specifically the butyrate ester, which modifies the pharmacokinetics of the hormone, affecting its half-life and duration of action.
Chemical Properties[edit | edit source]
Testosterone butyrate is characterized by the addition of a butyrate ester to the 17-beta hydroxyl group of testosterone. This modification increases the lipophilicity of the molecule, allowing it to be administered via intramuscular injection and providing a sustained release of testosterone into the bloodstream.
Mechanism of Action[edit | edit source]
As an androgen, testosterone butyrate binds to the androgen receptor in target tissues. This binding initiates a cascade of events leading to the expression of androgen-responsive genes, which are responsible for the development and maintenance of male secondary sexual characteristics and the promotion of muscle growth.
Clinical Use[edit | edit source]
Testosterone butyrate has been used in the treatment of hypogonadism in males, a condition characterized by low levels of endogenous testosterone. By supplementing with exogenous testosterone butyrate, normal physiological levels of testosterone can be restored, alleviating symptoms such as decreased libido, fatigue, and loss of muscle mass.
Pharmacokinetics[edit | edit source]
The butyrate ester prolongs the release of testosterone from the injection site, allowing for less frequent dosing compared to non-esterified testosterone. The pharmacokinetic profile of testosterone butyrate is similar to other testosterone esters, with a relatively slow absorption and a prolonged duration of action.
Side Effects[edit | edit source]
As with other anabolic steroids, testosterone butyrate can cause a range of side effects, particularly when used in supraphysiological doses. These may include acne, gynecomastia, testicular atrophy, and cardiovascular disease. Long-term use can also lead to liver damage and psychiatric effects.
Related Pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
