Testosterone furoate

Testosterone Furoate is a synthetic androgen and anabolic steroid and a testosterone ester. It is used in androgen replacement therapy primarily for the treatment of male hypogonadism, and is currently under research for use in male contraception.

Chemistry

Testosterone furoate, like other testosterone esters, is a prodrug of testosterone. It is synthesized by esterification of the 17β-hydroxyl group of testosterone with furoic acid.

Pharmacology

Testosterone furoate is administered via intramuscular injection. Once in the body, it is metabolized into testosterone and furoic acid. The testosterone then exerts its effects in the body, promoting the development and maintenance of male secondary sexual characteristics and influencing numerous other physiological processes.

Clinical Use

Testosterone furoate is used in androgen replacement therapy to treat male hypogonadism, a condition in which the body does not produce enough testosterone. It is also being researched for use in male contraception, as it has been shown to suppress spermatogenesis, the process of sperm production.

Side Effects

As with other testosterone esters, side effects of testosterone furoate can include acne, gynecomastia, and water retention. More serious side effects can include cardiovascular complications, such as heart attack and stroke, and psychiatric effects, such as mood swings and depression.

See Also

• Testosterone
• Androgen replacement therapy
• Anabolic steroid
• Hypogonadism
• Contraception