Testosterone valerate

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Testosterone valerate


Testosterone valerate is an ester of testosterone that is used in the treatment of hypogonadism and other conditions associated with low endogenous testosterone levels. It is a prodrug of testosterone, meaning it is metabolized in the body to produce testosterone.

Chemistry[edit | edit source]

Testosterone valerate is a synthetic androgen and anabolic steroid and a testosterone ester. It is more specifically a propionate ester of testosterone. Testosterone esters are less polar than free testosterone and are absorbed more slowly from the area of injection. Once in the bloodstream, they are converted back into free testosterone by the action of esterase enzymes.

Pharmacology[edit | edit source]

Testosterone valerate, like all testosterone esters, is converted by the body into testosterone. Testosterone is the primary male sex hormone and an anabolic steroid. It plays key roles in the development of male reproductive tissues such as the testis and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.

Medical uses[edit | edit source]

Testosterone valerate is used in androgen replacement therapy. It is specifically used to treat male hypogonadism and certain types of breast cancer in women. It may also be used to treat delayed puberty in boys, hypogonadism and impotence in men, and to reduce the effects of menopause in women.

Side effects[edit | edit source]

Like all medications, testosterone valerate can have side effects. These can include acne, breast enlargement, voice deepening, and changes in menstrual cycle in women. More serious side effects can include liver damage, heart problems, and behavioral changes.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD