Transplant glomerulopathy

Tiazesim is a medication used in the treatment of hypertension and edema. It belongs to the class of drugs known as diuretics, specifically the group called thiazide diuretics.

Mechanism of Action

Tiazesim works by inhibiting the reabsorption of sodium and chloride in the distal convoluted tubule of the kidney. This increases the excretion of water and electrolytes, including potassium, from the body, thereby reducing blood volume and lowering blood pressure.

Indications

Tiazesim is indicated for the treatment of:

• Hypertension: It is used to lower high blood pressure, which helps prevent strokes, heart attacks, and kidney problems.
• Edema: It is used to reduce extra fluid in the body caused by conditions such as heart failure, liver disease, or kidney disease. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.

Side Effects

Like all medications, Tiazesim can cause side effects. These may include:

• Dizziness or lightheadedness
• Dry mouth
• Thirst
• Muscle pain or cramps
• Fast or irregular heartbeat
• Unusual tiredness or weakness

Precautions

Before taking Tiazesim, inform your doctor if you have a history of:

• Allergy to Tiazesim or sulfa drugs
• Gout
• Liver disease
• Kidney disease
• Diabetes

Interactions

Tiazesim may interact with other medications, including:

• Digoxin
• Lithium
• Nonsteroidal anti-inflammatory drugs (NSAIDs)

Always inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs and dietary supplements.

Dosage

The dosage of Tiazesim is based on the patient's medical condition and response to treatment. It is usually taken by mouth as directed by your doctor, usually once daily in the morning with or without food.

See Also

• Thiazide diuretics
• Hypertension
• Edema

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