Tuberculosis verrucosa cutis

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Tuberculosis verrucosa cutis (TVC) is a form of cutaneous tuberculosis that results from an external inoculation of the tuberculosis bacillus in a person with moderate to high immunity against tuberculosis. This condition is also known as Lupus Verrucosus and Prosector's Wart.

File:Tuberculosis verrucosa cutis.jpg
Tuberculosis verrucosa cutis lesion on a patient's hand

Etiology[edit | edit source]

TVC is caused by Mycobacterium tuberculosis, the same bacterium that causes most cases of tuberculosis. The bacteria enter the body through a break in the skin, such as a cut or scrape. The infection is usually localized to the skin, but it can spread to other parts of the body.

Clinical Features[edit | edit source]

TVC typically presents as a single, warty lesion that slowly enlarges over time. The lesion is usually painless and may be accompanied by regional lymphadenopathy. The most common sites for TVC are the hands and lower extremities, but it can occur anywhere on the body.

Diagnosis[edit | edit source]

Diagnosis of TVC is based on clinical features, histopathological examination, and identification of Mycobacterium tuberculosis in the lesion. The Mantoux test, also known as the tuberculin skin test, is often positive in patients with TVC.

Treatment[edit | edit source]

Treatment of TVC involves a combination of antituberculous drugs for a period of 6 to 9 months. Surgical excision of the lesion may be necessary in some cases.

Epidemiology[edit | edit source]

TVC is a rare form of cutaneous tuberculosis. It is more common in developing countries and in people who work in occupations that involve contact with raw meat or fish, such as butchers and fishmongers.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD