Vaniprevir
Vaniprevir is a protease inhibitor used in the treatment of Hepatitis C. It is a second-generation protease inhibitor developed by Merck & Co., and is specifically designed to target the NS3/4A serine protease of the Hepatitis C virus.
Mechanism of Action[edit | edit source]
Vaniprevir works by inhibiting the NS3/4A serine protease, an enzyme that the Hepatitis C virus requires for replication. By blocking this enzyme, Vaniprevir prevents the virus from replicating within the host's liver cells.
Clinical Trials[edit | edit source]
Vaniprevir has undergone Phase II and Phase III clinical trials for the treatment of Hepatitis C. In these trials, it has shown significant efficacy in reducing viral load, particularly in patients with genotype 1 Hepatitis C, which is the most common form of the virus in the United States and Europe.
Side Effects[edit | edit source]
Common side effects of Vaniprevir include fatigue, headache, nausea, and diarrhea. In rare cases, it can cause severe skin reactions and liver damage.
Regulatory Status[edit | edit source]
As of 2021, Vaniprevir is approved for use in Japan, but not in the United States or Europe. In Japan, it is marketed under the brand name MK-7009.
See Also[edit | edit source]
 | This pharmacology-related article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
