Vantas
Vantas is a type of hormone therapy used in the treatment of advanced prostate cancer. It is a gonadotropin-releasing hormone (GnRH) agonist, which means it works by reducing the amount of testosterone produced by the body. This can slow the growth of prostate cancer cells, which often rely on testosterone to grow and spread.
Mechanism of Action[edit | edit source]
Vantas works by binding to GnRH receptors in the pituitary gland. This initially causes an increase in the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn stimulate the production of testosterone. However, with continuous use, Vantas causes a decrease in LH and FSH levels, leading to a reduction in testosterone production. This is known as a "flare" effect.
Side Effects[edit | edit source]
Like all medications, Vantas can cause side effects. Common side effects include hot flashes, fatigue, and decreased sexual desire. Less common but more serious side effects can include bone loss, increased risk of diabetes, and cardiovascular disease.
Usage and Dosage[edit | edit source]
Vantas is administered as an implant under the skin of the upper arm by a healthcare provider. The implant slowly releases the medication over a period of 12 months. Dosage is determined by the healthcare provider and is based on the patient's medical condition and response to therapy.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD