Wernicke Korsakoff syndrome

Wernicke-Korsakoff syndrome (WKS) is a type of brain disorder caused by a lack of vitamin B1 (thiamine). The syndrome is actually two separate conditions that can occur at the same time, Wernicke's encephalopathy and Korsakoff psychosis.

Causes

WKS is most commonly caused by alcohol abuse, but can also be associated with malnutrition, eating disorders, and certain medical conditions that make it hard for the body to absorb nutrients.

Symptoms

Symptoms of WKS can include memory loss, confusion, and hallucinations. In severe cases, it can cause coma or death.

Diagnosis

Diagnosis of WKS is based on a patient's medical history, physical examination, and neurological examination. Blood tests may be used to measure levels of thiamine and other vitamins and minerals.

Treatment

Treatment for WKS involves replacing the missing thiamine, often through intravenous therapy. This can help to improve symptoms, but some people may be left with permanent brain damage.

Prognosis

The prognosis for WKS varies. Some people may make a full recovery if the condition is caught early and treated promptly. However, in severe cases, the damage can be permanent and may lead to disability or death.

See also

• Alcohol-related brain damage
• Beriberi
• Thiamine deficiency

References

This vitamin-related article is a stub. You can help WikiMD by expanding it.