XCT-790

XCT-790 is a synthetic compound that acts as an inverse agonist for the Estrogen-related receptor alpha (ERRα). ERRα is a member of the nuclear receptor family of intracellular transcription factors and is closely related to the estrogen receptor, although it does not respond to estrogen. XCT-790 is used in scientific research to explore the role of ERRα in biology and medicine.

Chemistry

XCT-790 is a small molecule with a molecular weight of 394.4 g/mol. It is a synthetic compound, meaning it is not found naturally but is produced in a laboratory. The chemical formula of XCT-790 is C_24H_17F_3O_2.

Mechanism of Action

XCT-790 functions as an inverse agonist for ERRα. An inverse agonist is a type of drug that binds to the same receptor as an agonist but induces a pharmacological response opposite to that agonist. In the case of XCT-790, it binds to ERRα and inhibits its activity. This is in contrast to an agonist for ERRα, which would increase its activity.

Uses in Research

XCT-790 is primarily used in scientific research to study the role of ERRα. ERRα is involved in many biological processes, including energy homeostasis, cell proliferation, and differentiation. By using XCT-790 to inhibit ERRα, researchers can better understand its functions and the consequences of its inhibition.

Potential Therapeutic Applications

While XCT-790 is not currently used as a therapeutic drug in humans, its ability to inhibit ERRα suggests potential applications in the treatment of diseases where ERRα is overactive or dysregulated. These could include certain types of cancer, metabolic disorders, and cardiovascular diseases. However, more research is needed to fully understand the potential therapeutic applications of XCT-790.

Safety and Toxicity

As a research compound, XCT-790 is not intended for human consumption. Its safety and toxicity in humans have not been fully studied. Therefore, it should be handled with care and used only by trained professionals in a laboratory setting.