Zaltoprofen
Zaltoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used in the treatment of rheumatoid arthritis, osteoarthritis, and other inflammatory diseases. It is a propionic acid derivative and belongs to the class of fenamate NSAIDs. Zaltoprofen has been available in Japan since 1994.
Etymology[edit | edit source]
The name "Zaltoprofen" is derived from the chemical structure of the drug, which includes a benzene ring (Zalto) and a propionic acid group (profen).
Pharmacology[edit | edit source]
Zaltoprofen works by inhibiting the production of prostaglandins, chemicals that cause inflammation and pain in the body. It does this by blocking the action of the enzyme cyclooxygenase (COX), which is responsible for the production of prostaglandins. Zaltoprofen is a non-selective COX inhibitor, meaning it blocks both COX-1 and COX-2 enzymes.
Clinical Use[edit | edit source]
Zaltoprofen is used to relieve pain and inflammation in conditions such as rheumatoid arthritis and osteoarthritis. It is also used to treat other inflammatory diseases. The drug is usually taken orally in the form of tablets.
Side Effects[edit | edit source]
Like other NSAIDs, Zaltoprofen can cause side effects. These may include gastrointestinal problems such as stomach pain, nausea, and ulcers. It can also cause kidney problems and increase the risk of heart attack or stroke.
Related Terms[edit | edit source]
- Nonsteroidal anti-inflammatory drug
- Rheumatoid arthritis
- Osteoarthritis
- Inflammatory diseases
- Fenamate
- Prostaglandins
- Cyclooxygenase
- Gastrointestinal
- Kidney
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Contributors: Prab R. Tumpati, MD
