Zanaflex
Zanaflex is a brand name for the drug Tizanidine, a short-acting muscle relaxer. It is used to treat spasticity, a condition where muscles in your body spasm, cramp, or become tight due to medical problems such as multiple sclerosis or certain injuries to the spine. Zanaflex works by blocking nerve impulses (pain sensations) that are sent to your brain.
Pharmacology[edit | edit source]
Zanaflex is a central alpha-2 adrenergic agonist and is believed to work by decreasing nerve impulses that cause muscles to tighten, thereby reducing the frequency and severity of spasticity episodes.
Usage[edit | edit source]
Zanaflex is usually taken as needed for spasticity, up to three times a day. It can be taken with or without food, but taking it with food may increase the side effects of the medication. It is important to follow the dosing instructions provided by your healthcare provider.
Side Effects[edit | edit source]
Common side effects of Zanaflex include dry mouth, sleepiness, weakness, and fatigue. Less common side effects can include low blood pressure, slow heart rate, and liver function abnormalities. It is important to discuss any side effects with your healthcare provider.
Interactions[edit | edit source]
Zanaflex can interact with other medications, including certain blood pressure medications, Ciprofloxacin, and Fluvoxamine. It is important to tell your healthcare provider about all the medications you are taking.
Precautions[edit | edit source]
Zanaflex should be used with caution in patients with liver disease, as it is metabolized by the liver. It should also be used with caution in patients with low blood pressure or slow heart rate.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD