3,4-Methylenedioxy-N-hydroxyamphetamine

3,4-Methylenedioxy-N-hydroxyamphetamine (MDOH) is a lesser-known psychedelic drug and a substituted amphetamine. MDOH was first synthesized by Alexander Shulgin. In his book PiHKAL, the dosage range is listed as 100-160 mg, and the duration is listed as 3–6 hours. Shulgin reports that MDOH is believed to be a psychedelic and an entactogen.

History[edit | edit source]

MDOH was first synthesized and studied by Alexander Shulgin in the 1970s. Shulgin included MDOH in a series of compounds related to MDMA that he synthesized for potential therapeutic use.

Chemistry[edit | edit source]

MDOH is a substituted amphetamine, meaning it is an amphetamine molecule which has been modified. In this case, the modification is the addition of a methylenedioxy group and a hydroxy group. This changes the properties of the drug and makes it different from other amphetamines.

Pharmacology[edit | edit source]

The pharmacological properties of MDOH are not well-studied. However, it is believed to act as a serotonin releasing agent, similar to other drugs in the MDMA family. This means it increases the levels of serotonin in the brain, which can lead to feelings of happiness, empathy, and euphoria.

Effects[edit | edit source]

The effects of MDOH are not well-documented, as it is not commonly used. However, it is believed to produce effects similar to those of other entactogens and psychedelics, such as increased empathy, altered perception, and hallucinations.

Legal Status[edit | edit source]

The legal status of MDOH varies by country. In the United States, it is not specifically listed as a controlled substance, but it could potentially be considered an analog of MDMA, which is a Schedule I drug.

See Also[edit | edit source]

Template:Psychedelic drug Template:Substituted amphetamine

3,4-Methylenedioxy-N-hydroxyamphetamine Resources
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