3-Hydroxybenzoic acid

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Overview of 3-Hydroxybenzoic acid


3-Hydroxybenzoic acid[edit | edit source]

Chemical structure of 3-Hydroxybenzoic acid

3-Hydroxybenzoic acid is an organic compound with the formula C_H_O_. It is one of the three isomeric hydroxybenzoic acids, the others being 2-hydroxybenzoic acid (salicylic acid) and 4-hydroxybenzoic acid. This compound is a phenolic acid and is characterized by a hydroxyl group (-OH) attached to the benzene ring of benzoic acid at the third position.

Chemical Properties[edit | edit source]

3-Hydroxybenzoic acid is a white crystalline solid that is slightly soluble in water but more soluble in organic solvents such as ethanol and ether. It exhibits typical properties of phenolic acids, including the ability to form esters and salts. The presence of the hydroxyl group influences its acidity, making it more acidic than benzoic acid itself.

Biological Significance[edit | edit source]

In biological systems, 3-hydroxybenzoic acid can be found as a metabolite in the degradation of aromatic compounds. It is involved in various biochemical pathways and can be produced by certain microorganisms as part of their metabolic processes. This compound is also studied for its potential antioxidant properties and its role in plant defense mechanisms.

Synthesis[edit | edit source]

3-Hydroxybenzoic acid can be synthesized through several methods, including the Kolbe-Schmitt reaction, which involves the carboxylation of phenolates. Another method involves the hydroxylation of benzoic acid using oxidizing agents. These synthetic routes are important for producing the compound in laboratory settings for research and industrial applications.

Applications[edit | edit source]

This compound is used in the synthesis of various pharmaceuticals, dyes, and polymers. Its derivatives are explored for their potential use in medicine due to their biological activity. Additionally, 3-hydroxybenzoic acid is used as a precursor in the synthesis of more complex organic compounds.

Related Compounds[edit | edit source]

Related Pages[edit | edit source]

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Contributors: Prab R. Tumpati, MD