4-Methyldiphenhydramine

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4-Methyldiphenhydramine is a chemical compound that belongs to the class of organic compounds known as diphenhydramines. Diphenhydramines are compounds containing a diphenhydramine moiety, which is structurally characterized by the presence of a 2-(diphenylmethoxy)-N,N-dimethylethanamine combined with a benzhydryl ether moiety.

Chemical Properties[edit | edit source]

4-Methyldiphenhydramine is a derivative of diphenhydramine, a first-generation H1-antihistamine that is used to treat a variety of conditions such as allergies, insomnia, and nausea. The addition of a methyl group to the diphenhydramine molecule results in 4-Methyldiphenhydramine. This modification can potentially alter the pharmacological properties of the compound, although the specific effects of this modification are not well-studied.

Pharmacology[edit | edit source]

Like other diphenhydramines, 4-Methyldiphenhydramine is thought to exert its effects by blocking the action of histamine at H1 receptors. This can result in a variety of effects, including sedation, anti-nausea, and anti-allergy effects. However, the specific pharmacological properties of 4-Methyldiphenhydramine, including its potency and efficacy relative to other diphenhydramines, are not well-known.

Potential Uses[edit | edit source]

Given its structural similarity to diphenhydramine, 4-Methyldiphenhydramine may have potential uses in the treatment of conditions such as allergies, insomnia, and nausea. However, further research is needed to determine the safety and efficacy of this compound in these contexts.

Safety and Toxicity[edit | edit source]

The safety and toxicity of 4-Methyldiphenhydramine are not well-studied. As with any chemical compound, exposure to 4-Methyldiphenhydramine could potentially result in adverse effects. Therefore, appropriate safety precautions should be taken when handling this compound.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD