AR-C

AR-C is a chemical compound that is used in scientific research. It is a potent and selective agonist for the GPR119 receptor, which is involved in the regulation of glucose homeostasis and energy balance. AR-C has been shown to increase insulin secretion and improve glucose tolerance in animal models, making it a potential therapeutic target for the treatment of type 2 diabetes.

Chemical Structure[edit | edit source]

AR-C is a small molecule with a molecular weight of 503.6 g/mol. It has a complex chemical structure, consisting of a pyrazole ring attached to a phenyl group, which is further linked to a piperidine ring via a carbonyl group. The molecule also contains several fluorine atoms, which contribute to its high potency and selectivity for the GPR119 receptor.

Mechanism of Action[edit | edit source]

AR-C acts as an agonist at the GPR119 receptor, a G protein-coupled receptor that is expressed in the pancreas and the gastrointestinal tract. Activation of this receptor leads to an increase in intracellular cyclic AMP levels, which in turn stimulates insulin secretion from the beta cells of the pancreas. This results in improved glucose tolerance and may help to regulate energy balance.

Therapeutic Potential[edit | edit source]

Due to its effects on insulin secretion and glucose tolerance, AR-C has been investigated as a potential treatment for type 2 diabetes. Animal studies have shown promising results, with AR-C treatment leading to improved glucose control and reduced body weight. However, further research is needed to determine the safety and efficacy of this compound in humans.

References[edit | edit source]

AR-C Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.