Anti-IgLON5 disease
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| Specialty | immunology |
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Anti-IgLON5 disease is a neurodegenerative autoimmune disease. It is marked by parasomnias and chorea.[1][2][3][4][5]
IgLON5 is a cell surface adhesion molecule.[6]
Prevalence of the HLA-DRB1*10:01 allele was greatly increased in people with anti-IgLON5 disease.[1]
References[edit | edit source]
- ↑ Jump up to: 1.0 1.1 , Clinical manifestations of the anti-IgLON5 disease, Neurology, Vol. 88(Issue: 18), pp. 1736–1743, DOI: 10.1212/WNL.0000000000003887, PMID: 28381508, PMC: 5409845,
- ↑ , A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series, characterisation of the antigen, and post-mortem study, The Lancet Neurology, Vol. 13(Issue: 6), pp. 575–586, DOI: 10.1016/S1474-4422(14)70051-1, PMID: 24703753, PMC: 4104022,
- ↑ , IgLON5 antibody, Neurology - Neuroimmunology Neuroinflammation, Vol. 4(Issue: 5), pp. e385, DOI: 10.1212/NXI.0000000000000385, PMID: 28761904, PMC: 5515599,
- ↑ , Understanding anti-IgLON5 disease, Neurology - Neuroimmunology Neuroinflammation, Vol. 4(Issue: 5), pp. e393, DOI: 10.1212/NXI.0000000000000393, PMID: 28852690, PMC: 5570673,
- ↑ NEJM Journal Watch: Summaries of and commentary on original medical and scientific articles from key medical journals Full text, www.jwatch.org,
- ↑ IGLON5 Gene - GeneCards | IGLO5 Protein | IGLO5 Antibody Full text, www.genecards.org,
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