Buphedrone

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Buphedrone


Buphedrone is a psychoactive drug and research chemical of the substituted phenethylamine, substituted cathinone and substituted methylenedioxyphenethylamine classes. It was first synthesized in 1928 but its potential for abuse was not recognized until the mid-2000s.

Chemistry[edit | edit source]

Buphedrone, also known as α-methylamino-butyrophenone, is a β-keto amphetamine analogue of MDPV. It has a chemical formula of C11H15NO and a molecular weight of 177.242 g/mol. The compound is a white crystalline powder at room temperature.

Pharmacology[edit | edit source]

The pharmacodynamics of buphedrone are not fully understood. However, it is known to act as a norepinephrine-dopamine reuptake inhibitor (NDRI), similar to other cathinones. This means it increases the levels of the neurotransmitters norepinephrine and dopamine in the brain by inhibiting their reuptake into neurons.

Effects[edit | edit source]

The effects of buphedrone are similar to those of other stimulants and include increased alertness, euphoria, increased sociability, and increased energy. However, it can also cause negative effects such as anxiety, paranoia, and increased heart rate.

Legal Status[edit | edit source]

The legal status of buphedrone varies by country. In the United States, it is a Schedule I controlled substance, meaning it has a high potential for abuse and no accepted medical use. In the United Kingdom, it is a Class B drug under the Misuse of Drugs Act 1971.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD