CGS-13767

CGS-13767 is a drug of the amino acid class. It acts as a competitive antagonist at the NMDA receptor and has neuroprotective effects. It has been investigated for its potential use in the treatment of stroke.

Pharmacology

CGS-13767 is a competitive antagonist at the NMDA receptor, a type of ionotropic glutamate receptor. By blocking the action of the neurotransmitter glutamate at these receptors, CGS-13767 can reduce the excitotoxicity caused by excessive glutamate release following brain injury.

Clinical significance

The neuroprotective effects of CGS-13767 have led to its investigation for potential use in the treatment of stroke. In animal models, it has been shown to reduce the size of infarcts and improve neurological outcomes.

See also

• NMDA receptor antagonist
• Neuroprotection
• Stroke

References

CGS-13767 Resources
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