Cervical squamous intraepithelial neoplasia 1

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Cervical Squamous Intraepithelial Neoplasia 1
Synonyms CIN 1
Pronounce N/A
Specialty N/A
Symptoms Often asymptomatic
Complications Progression to higher-grade lesions
Onset Reproductive age
Duration Variable
Types N/A
Causes Human papillomavirus (HPV) infection
Risks Multiple sexual partners, early sexual activity
Diagnosis Pap smear, Colposcopy, Biopsy
Differential diagnosis N/A
Prevention N/A
Treatment Observation, Cryotherapy, LEEP
Medication N/A
Prognosis Good with monitoring
Frequency Common
Deaths N/A


Cervical Squamous Intraepithelial Neoplasia 1 (CIN 1) is a low-grade lesion of the cervix that is considered a precursor to cervical cancer. It is characterized by mild dysplasia, where there are slight abnormalities in the size, shape, and number of cells on the surface of the cervix.

Causes[edit | edit source]

CIN 1 is primarily caused by infection with certain types of human papillomavirus (HPV), particularly HPV types 16 and 18, which are known to be high-risk for cervical cancer. Other risk factors include having multiple sexual partners, early onset of sexual activity, and a weakened immune system.

Symptoms[edit | edit source]

CIN 1 is often asymptomatic, meaning it does not usually cause any noticeable symptoms. It is typically detected through routine Pap smear tests, which are part of regular cervical cancer screening programs.

Diagnosis[edit | edit source]

The diagnosis of CIN 1 is made through a combination of Pap smear, colposcopy, and biopsy. During a Pap smear, cells from the cervix are collected and examined under a microscope. If abnormalities are detected, a colposcopy may be performed, which involves using a special microscope to closely examine the cervix. A biopsy may be taken to confirm the diagnosis.

Treatment[edit | edit source]

In many cases, CIN 1 does not require immediate treatment and may resolve on its own. Patients are often monitored with regular follow-up Pap smears and colposcopies. If treatment is necessary, options include cryotherapy, which involves freezing the abnormal cells, or the loop electrosurgical excision procedure (LEEP), which removes the abnormal tissue using a wire loop.

Prognosis[edit | edit source]

The prognosis for CIN 1 is generally good, especially with regular monitoring. Most cases do not progress to higher-grade lesions or cervical cancer. However, it is important for individuals with CIN 1 to adhere to follow-up care to ensure any changes are detected early.

See also[edit | edit source]

References[edit | edit source]


External links[edit | edit source]

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Contributors: Prab R. Tumpati, MD