Chittaranjan Yajnik

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Dr. Yajnik (13 February 2020)

Chittaranjan Yajnik is a distinguished Indian medical researcher known for his pioneering work in the field of diabetes mellitus and its correlation with genetic factors, particularly in the context of the Indian population. His research has significantly contributed to the understanding of the high susceptibility of Indians to Type 2 diabetes and has shed light on the nutritional, genetic, and environmental factors influencing this condition.

Early Life and Education[edit | edit source]

Chittaranjan Yajnik was born in India, where he also received his primary and secondary education. He pursued his medical degree (MBBS) from a reputable medical college in India, followed by specialization in internal medicine and later in endocrinology. His early interest in public health and epidemiology guided his career towards research in chronic diseases, with a focus on diabetes.

Career and Research[edit | edit source]

Yajnik's career has been marked by his tenure at the King Edward Memorial Hospital and Research Centre in Pune, India, where he has led the Diabetes Unit. His work has been pivotal in identifying the genetic predisposition of the Indian population to insulin resistance and Type 2 diabetes. Yajnik's research has highlighted the concept of the "thin-fat" Indian, a phenotype characterized by lower muscle mass and higher body fat percentage compared to other populations, contributing to increased insulin resistance and susceptibility to diabetes.

One of the hallmark studies led by Yajnik involved the comprehensive analysis of the COX7A1 gene and its association with insulin resistance among Indians. His studies have also explored the impact of maternal nutrition and low vitamin B12 levels on the epigenetic modifications in the fetus, leading to a higher risk of diabetes and other metabolic conditions in adulthood.

Contributions and Impact[edit | edit source]

Yajnik's contributions extend beyond the realm of diabetes research. He has been actively involved in public health initiatives aimed at improving the nutritional status of pregnant women and young children as a preventive measure against chronic diseases. His advocacy for policy changes to combat the rising tide of diabetes in India has been influential in shaping public health strategies and nutritional guidelines.

His work has been recognized globally, with numerous awards and honors bestowed upon him for his contributions to medical research and public health. Yajnik has also been a prolific writer, contributing to various scientific journals and publications to disseminate his findings and insights on diabetes and related conditions.

Legacy[edit | edit source]

Chittaranjan Yajnik's legacy in the field of diabetes research is marked by his relentless pursuit of understanding the complex interplay of genetic, nutritional, and environmental factors in the onset of diabetes. His work has not only advanced scientific knowledge but has also had a tangible impact on public health policies and practices, particularly in the Indian context.


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Contributors: Prab R. Tumpati, MD