Cortivazol

Cortivazol

Cortivazol is a potent synthetic glucocorticoid, a class of steroid hormones that are produced in the adrenal cortex of vertebrates. It is used in medicine for its anti-inflammatory and immunosuppressive properties.

Pharmacology

Cortivazol works by binding to the glucocorticoid receptor, a type of nuclear receptor that is activated by binding to glucocorticoid hormones. This binding triggers a series of events that leads to the suppression of the immune system, reducing inflammation and suppressing the body's immune response.

Medical uses

Cortivazol is used in the treatment of a variety of conditions that involve inflammation or an overactive immune system. These include rheumatoid arthritis, asthma, allergies, and certain autoimmune diseases. It is also used in the treatment of certain types of cancer, where it can help to reduce inflammation and suppress the immune system's response to the cancer cells.

Side effects

Like all glucocorticoids, cortivazol can have a number of side effects. These can include weight gain, osteoporosis, diabetes, and an increased risk of infection. Long-term use can also lead to Cushing's syndrome, a condition characterized by a round face, upper body obesity, and thin skin.

History

Cortivazol was first synthesized in the 1970s as part of a search for more potent glucocorticoids. It was found to be significantly more potent than other glucocorticoids available at the time, and was subsequently developed for medical use.

See also

• List of glucocorticoids
• Glucocorticoid receptor
• Adrenal cortex