Cushingoid
Cushingoid is a term used to describe the physical appearance and symptoms associated with long-term use of glucocorticoid hormones. These symptoms can include obesity, a rounded face, increased fat around the neck, and thinning arms and legs.
Symptoms[edit | edit source]
The symptoms of Cushingoid can vary, but they often include:
- Obesity - This is often centered in the face, chest, and abdomen, with relatively slender arms and legs.
- Moon face - This is a rounded, puffy appearance of the face.
- Buffalo hump - This is a lump of fat on the back of the neck.
- Skin changes - These can include purple stretch marks, thinning skin, and easy bruising.
- Muscle weakness
- High blood pressure
- High blood sugar
- Osteoporosis
- Mental changes - These can include depression, anxiety, and irritability.
Causes[edit | edit source]
Cushingoid is most commonly caused by the long-term use of glucocorticoid hormones, such as prednisone, for the treatment of diseases like asthma, rheumatoid arthritis, and lupus. It can also be caused by the body's overproduction of cortisol, a hormone that helps the body respond to stress.
Diagnosis[edit | edit source]
The diagnosis of Cushingoid is based on the patient's medical history, physical examination, and laboratory tests. These tests may include blood tests to measure levels of cortisol and other hormones, and imaging tests to look for abnormalities in the adrenal or pituitary glands.
Treatment[edit | edit source]
The treatment of Cushingoid depends on the underlying cause. If it is caused by the use of glucocorticoid hormones, the dose may need to be reduced or the medication may need to be stopped. If it is caused by the body's overproduction of cortisol, treatment may include surgery, radiation therapy, or medication.
See also[edit | edit source]
Cushingoid Resources | |
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Contributors: Prab R. Tumpati, MD