Diatrizoate sodium

Diatrizoate Sodium is a type of contrast agent used in medical imaging to enhance the visibility of structures or fluids within the body. It is also known as Hypaque, Urografin, and Gastrografin.

Overview

Diatrizoate Sodium is a water-soluble, iodinated, radiopaque contrast medium with a high osmolality. It is used in various diagnostic procedures such as intravenous urography, angiography, computed tomography, and hysterosalpingography.

Mechanism of Action

Diatrizoate Sodium works by blocking x-rays. When it is injected or swallowed, it travels through the bloodstream or the gastrointestinal tract respectively. The iodine in Diatrizoate Sodium absorbs the x-rays and allows the radiologist to see the structures or fluids more clearly on the x-ray film or computer monitor.

Side Effects

Like all medications, Diatrizoate Sodium can cause side effects. Common side effects include nausea, vomiting, diarrhea, and a feeling of warmth or flushing. Serious side effects are rare but can include allergic reactions, kidney damage, and thyroid dysfunction.

Contraindications

Diatrizoate Sodium should not be used in patients with a known hypersensitivity to iodinated contrast agents, in patients with severe kidney disease, or in patients with an overactive thyroid gland.

See Also

• Contrast agent
• Medical imaging
• Iodine
• Radiology