FGI-104

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FGI-104 is the name of an experimental broad-spectrum antiviral drug, with activity against a range of viruses including Hepatitis B, Hepatitis C, HIV, Ebola virus and Venezuelan equine encephalitis virus. [1]

Mechanism[edit | edit source]

The drug acts by inhibiting the protein TSG101, which transports newly manufactured virions to the exterior of an infected cell, thus breaking the replication cycle of the virus. In pre-clinical studies, FGI-104 has been shown to protect mice from Ebola virus disease.[2]

See also[edit | edit source]

References[edit | edit source]


Portions of content adapted from Wikipedia's article on FGI-104 which is released under the CC BY-SA 3.0.

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Contributors: Prab R. Tumpati, MD