Icosagen (company)

Icosagen Cell Factory OÜ is a biotechnology company based in Estonia that specializes in the research, development, and production of recombinant proteins, antibodies, and virus-like particles (VLPs) for use in research, diagnostics, and therapeutic applications. Founded in the early 2000s, Icosagen has established itself as a key player in the global biotech industry, leveraging its proprietary cell expression systems and molecular biology expertise.

Overview

Icosagen operates at the forefront of biotechnology, utilizing cutting-edge technologies to engineer cell lines that produce high yields of complex biological molecules. The company's services encompass the entire development process, from gene synthesis and vector construction to protein expression, purification, and characterization. Icosagen's technologies are applicable in a wide range of fields, including immunology, oncology, and vaccine development, making it a valuable partner for both academic research institutions and pharmaceutical companies.

Technology and Services

One of the core technologies developed by Icosagen is its proprietary QMCF Technology (Quail-based MultiCopy Expression System), which allows for the efficient expression of recombinant proteins in quail cells. This system is designed to overcome the limitations of traditional mammalian expression systems by offering higher expression levels, faster development times, and the ability to produce proteins with complex post-translational modifications.

In addition to its QMCF Technology, Icosagen offers a range of services, including:

• Gene Synthesis and Vector Construction: Custom design and synthesis of genetic constructs for optimal protein expression.
• Protein Expression and Purification: Utilization of various expression systems (bacterial, yeast, insect, and mammalian cells) to produce high-purity recombinant proteins.
• Antibody Development: Generation of monoclonal and polyclonal antibodies for research and therapeutic use.
• Virus-like Particles (VLPs) Production: Engineering of VLPs for use in vaccine development and other applications.

Research and Development

Icosagen is actively involved in research and development projects aimed at advancing the field of biotechnology and developing new applications for its technologies. The company collaborates with academic institutions and industry partners on projects ranging from the discovery of novel therapeutic targets to the development of next-generation vaccines.

Facilities

Icosagen's headquarters and main research facilities are located in Tartu, Estonia. The company's state-of-the-art laboratories are equipped with the latest biotechnological equipment, enabling high-throughput screening, protein engineering, and analytical services.

Regulatory Compliance

Icosagen adheres to strict regulatory standards to ensure the quality and safety of its products and services. The company operates in compliance with Good Manufacturing Practice (GMP) guidelines, which are critical for the production of pharmaceuticals and therapeutic agents.

Conclusion

Icosagen Cell Factory OÜ represents a significant force in the biotechnology industry, with its innovative technologies and comprehensive range of services. By focusing on the development of high-quality recombinant proteins, antibodies, and VLPs, Icosagen is contributing to the advancement of scientific research and the development of new therapies for various diseases.

Icosagen (company) Resources
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