Myoglobinuria

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Myoglobinuria is a medical condition characterized by the presence of myoglobin in the urine, usually associated with muscle destruction. Myoglobin is an iron- and oxygen-binding protein found in the muscle tissue of most mammals. When the muscle tissue is damaged, myoglobin is released into the bloodstream and eventually appears in the urine, causing it to turn a dark brown color.

Causes[edit | edit source]

Myoglobinuria can be caused by any condition that results in muscle damage, including:

Symptoms[edit | edit source]

The primary symptom of myoglobinuria is dark or brown urine. Other symptoms can include muscle weakness or pain, fatigue, and in severe cases, kidney failure.

Diagnosis[edit | edit source]

Diagnosis of myoglobinuria typically involves a urine test to detect the presence of myoglobin. Blood tests may also be used to measure levels of creatine kinase, an enzyme that is released into the bloodstream when muscle tissue is damaged.

Treatment[edit | edit source]

Treatment for myoglobinuria primarily involves treating the underlying cause of the muscle damage. This may include rehydration to help flush the myoglobin out of the kidneys, medications to control symptoms, and in severe cases, dialysis to remove the myoglobin from the blood.

See also[edit | edit source]


Myoglobinuria Resources

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Contributors: Prab R. Tumpati, MD, Dr.T