Non-small-cell lung cancer

Non-small-cell lung carcinoma (NSCLC) is the most common type of lung cancer, making up 85-90% of all cases. NSCLC primarily includes adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. It is generally a disease of the elderly and is closely correlated with a history of tobacco smoking.

Symptoms

The symptoms of NSCLC are not specific and may include cough, shortness of breath, hemoptysis, and chest pain. In many cases, the cancer is discovered on routine imaging or incidentally when imaging for another reason.

Diagnosis

Diagnosis of NSCLC involves a series of tests, including imaging studies, biopsies, and molecular testing. Imaging studies such as CT scans and PET scans are often used to identify the location and extent of the cancer. Biopsies can be performed in various ways and are used to confirm the diagnosis and determine the cancer's histological type. Molecular testing is used to identify specific genetic mutations that may be present in the cancer cells.

Treatment

Treatment of NSCLC depends on the stage of the disease, the patient's overall health, and the patient's personal preferences. Treatment options may include surgery, radiation therapy, chemotherapy, targeted therapy, and immunotherapy. In some cases, a combination of these treatments may be used.

Prognosis

The prognosis for NSCLC varies widely depending on the stage of the disease at diagnosis. Early-stage cancers that can be surgically removed have a better prognosis than advanced cancers that have spread to other parts of the body.

See also

• Small cell lung carcinoma
• Lung cancer screening
• Lung cancer staging

Non-small-cell lung cancer Resources
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