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Template:Metabotropic glutamate receptor modulators
From WikiMD.com - Food, Medicine & Wellness Encyclopedia
Metabotropic glutamate receptor
modulators
Group I
mGluR
1
*
Agonists:
ACPD
DHPG
Glutamate
Ibotenic acid
Quisqualic acid
Ro01-6128
Ro67-4853
Ro67-7476
VU-71
Theanine
Antagonists:
BAY 36-7620
CPCCOEt
Cyclothiazide
LY-367,385
LY-456,236
MCPG
NPS-2390
mGluR
5
*
Agonists:
ACPD
ADX-47273
CDPPB
CHPG
DFB
DHPG
Glutamate
Ibotenic acid
Quisqualic acid
VU-1545
;
Positive allosteric modulators:
LSN2463359
Antagonists:
CTEP
DMeOB
LY-344,545
Mavoglurant
MCPG
NPS-2390
Remeglurant
SIB-1757
SIB-1893
;
Negative allosteric modulators:
AZD9272
Basimglurant
Dipraglurant
Fenobam
GRN-529
MPEP
MTEP
Raseglurant
Group II
mGluR
2
*
Agonists:
BINA
CBiPES
DCG-IV
Eglumegad
Glutamate
Ibotenic acid
LY-379,268
LY-404,039 (pomaglumetad)
LY-487,379
LY-566,332
MGS-0028
Pomaglumetad methionil (LY-2140023)
Talaglumetad
;
Positive allosteric modulators:
JNJ-40411813 (ADX-71149)
Antagonists:
APICA
CECXG
EGLU
HYDIA
LY-307,452
LY-341,495
MCPG
MGS-0039
PCCG-4
;
Negative allosteric modulators:
Decoglurant
RO4491533
mGluR
3
*
Agonists:
CBiPES
DCG-IV
Eglumegad
Glutamate
Ibotenic acid
LY-379,268
LY-404,039 (pomaglumetad)
LY-487,379
MGS-0028
Pomaglumetad methionil (LY-2140023)
Talaglumetad
Antagonists:
APICA
CECXG
EGLU
HYDIA
LY-307,452
LY-341,495
MCPG
MGS-0039
;
Negative allosteric modulators:
Decoglurant
RO4491533
Group III
mGluR
4
*
Agonists:
Glutamate
L
-AP4
LSP2-9166
PHCCC
VU-001,171
VU-0155,041
;
Positive allosteric modulators:
Foliglurax
MPEP
Antagonists:
CPPG
MAP4
MPPG
MSOP
MTPG
UBP-1112
mGluR
6
*
Agonists:
Glutamate
L
-AP4
Antagonists:
CPPG
MAP4
MPPG
MSOP
MTPG
UBP-1112
mGluR
7
*
Agonists:
AMN082
Glutamate
L
-AP4
LSP2-9166
Antagonists:
CPPG
MAP4
MMPIP
MPPG
MSOP
MTPG
UBP-1112
XAP044
;
Negative allosteric modulators:
ADX71743
mGluR
8
*
Agonists:
DCPG
Glutamate
L
-AP4
;
Positive allosteric modulators:
AZ12216052
Antagonists:
CPPG
MAP4
MPPG
MSOP
MTPG
UBP-1112
See also:
Receptor/signaling modulators
•
Ionotropic glutamate receptor modulators
•
Glutamate metabolism/transport modulators
Category
:
Drug templates by receptor, channel, or pump