Ro01-6128
Ro01-6128 is a pharmacological compound that belongs to the class of benzodiazepine drugs. It is a psychoactive drug that possesses anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, and amnestic properties.
Pharmacology[edit | edit source]
Ro01-6128 is a benzodiazepine receptor agonist. It binds to the GABA (gamma-aminobutyric acid) receptors in the brain, enhancing the effects of this inhibitory neurotransmitter and leading to sedative and anxiolytic effects.
Medical Uses[edit | edit source]
Ro01-6128 is primarily used for the treatment of anxiety disorders, insomnia, seizures, and muscle spasms. It is also used as a premedication for medical or dental procedures to induce sedation and amnesia.
Side Effects[edit | edit source]
Common side effects of Ro01-6128 include drowsiness, dizziness, and impaired coordination. Long-term use can lead to physical dependence and withdrawal symptoms upon discontinuation.
History[edit | edit source]
Ro01-6128 was first synthesized in the 1970s by Roche, a Swiss multinational healthcare company. It is part of the larger family of benzodiazepine drugs, which were first discovered in the 1950s.
See Also[edit | edit source]
 | This pharmacology-related article is a stub. You can help WikiMD by expanding it. |
Benzodiazipines[edit source]
- Alprazolam
- Chlordiazepoxide
- Diazepam (Oral)
- Estazolam
- Flurazepam
- Lorazepam
- Midazolam
- Oxazepam
- Quazepam
- Temazepam
- Triazolam
Anticonvulsants Drugs[edit source]
Drug class for Ro01-6128[edit source]
Sedatives and Hypnotics[edit source]
- Herbals
- Chamomile (Matricaria recutita)
- Hops (Humulus lupulus)
- Lavender (Lavandula angustifolia)
- Passionflower (Passiflora incarnata)
- Valerian (Valeriana officinalis)
- Melatonin and its Analogues
Miscellaneous Agents
- Buspirone
- Chloral hydrate
- Doxepin
- Meprobamate
- Sodium Oxybate (Narcolepsy Agent)
- Suvorexant
- Baclofen
- Carisoprodol
- Chlorzoxazone
- Cyclobenzaprine
- Dantrolene
- Metaxalone
- Methocarbamol
- Orphenadrine
- Tizanidine
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Contributors: Prab R. Tumpati, MD
