Toxic multinodular goitre

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(Redirected from Toxic multinodular goiter)

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Thyroid condition characterized by an enlarged thyroid gland with multiple nodules


Toxic multinodular goitre
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Synonyms Plummer's disease
Pronounce N/A
Field Endocrinology
Symptoms Hyperthyroidism, goitre, weight loss, tremors, palpitations
Complications Thyroid storm, atrial fibrillation, osteoporosis
Onset
Duration
Types N/A
Causes Iodine deficiency, genetic factors
Risks
Diagnosis Thyroid function tests, ultrasound, radioactive iodine uptake test
Differential diagnosis Graves' disease, thyroiditis
Prevention N/A
Treatment Antithyroid medication, radioactive iodine therapy, thyroidectomy
Medication Methimazole, propylthiouracil
Prognosis
Frequency
Deaths


Toxic multinodular goitre (TMNG), also known as Plummer's disease, is a condition characterized by an enlarged thyroid gland with multiple nodules that produce excess thyroid hormone, leading to hyperthyroidism. This condition is more common in older adults and in regions with iodine deficiency.

Signs and symptoms[edit | edit source]

The symptoms of toxic multinodular goitre are primarily those of hyperthyroidism and may include:

Complications[edit | edit source]

If left untreated, toxic multinodular goitre can lead to serious complications such as:

Causes[edit | edit source]

The exact cause of toxic multinodular goitre is not fully understood, but it is believed to be related to:

Diagnosis[edit | edit source]

Diagnosis of toxic multinodular goitre typically involves:

Differential diagnosis[edit | edit source]

Conditions that may present similarly and need to be differentiated from toxic multinodular goitre include:

Treatment[edit | edit source]

Treatment options for toxic multinodular goitre include:

See also[edit | edit source]

References[edit | edit source]






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