Ufenamate

Ufenamate

Ufenamate is a non-steroidal anti-inflammatory drug (NSAID) that is used primarily in the treatment of inflammation and pain associated with various conditions. It is a member of the fenamate class of NSAIDs, which also includes mefenamic acid and meclofenamic acid. Ufenamate is not widely used and is most commonly available in topical form.

Pharmacology

Ufenamate works by inhibiting the enzymes cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). These enzymes are involved in the production of prostaglandins, which are chemicals that promote inflammation, pain, and fever. By inhibiting these enzymes, ufenamate reduces the levels of prostaglandins, thereby reducing inflammation and pain.

Clinical Use

Ufenamate is used to treat a variety of conditions that cause pain and inflammation, such as arthritis, muscle sprains and strains, and menstrual pain. It is also used to reduce pain and inflammation following surgery. Because it is available in topical form, it is often used for conditions that affect the skin, such as sunburn and insect bites.

Side Effects

Like all NSAIDs, ufenamate can cause side effects. The most common side effects are skin irritation and rash at the application site. Less common side effects can include stomach upset, nausea, and diarrhea. Rare but serious side effects can include stomach ulcers, bleeding, and kidney damage.

See Also

• Non-steroidal anti-inflammatory drug
• Fenamate
• Mefenamic acid
• Meclofenamic acid

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