ATC code A04

ATC codes
A Alimentary tract and metabolism
	A01 Stomatological preparations
	A02 Drugs for acid related disorders
	A03 Drugs for functional gastrointestinal disorders
	A04 Antiemetics and antinauseants
	A05 Bile and liver therapy
	A06 Drugs for constipation
	A07 Antidiarrheals, intestinal anti-inflammatory/anti-infective agents
	A08 Antiobesity preparations, excluding diet products
	A09 Digestives, including enzymes
	A10 Drugs used in diabetes
	A11 Vitamins
	A12 Mineral supplements
	A13 Tonics
	A14 Anabolic agents for systemic use
	A15 Appetite stimulants
	A16 Other alimentary tract and metabolism products
A B C D G H QI J L M N P R S V ; (Hover over links to see titles) ;

ATC code A04 is a section of the Anatomical Therapeutic Chemical Classification System (ATC), a system used for the classification of drugs and other medical products. This section is specifically designated for antiemetics and antinauseants, which are medications used to prevent and treat nausea and vomiting.

Classification[edit | edit source]

The ATC code A04 is divided into several subgroups, each representing a different class of antiemetic and antinauseant medications. These subgroups include:

A04A - Antiemetics and antinauseants

A04AA - Serotonin (5-HT3) antagonists[edit | edit source]

A04AA01 - Ondansetron
A04AA02 - Granisetron
A04AA03 - Tropisetron
A04AA04 - Dolasetron
A04AA05 - Palonosetron

A04AB - Dopamine antagonists[edit | edit source]

A04AB01 - Metoclopramide
A04AB02 - Domperidone
A04AB03 - Droperidol

A04AC - Other antiemetics[edit | edit source]

A04AC01 - Aprepitant
A04AC02 - Fosaprepitant
A04AC03 - Netupitant
A04AC04 - Rolapitant

Uses[edit | edit source]

Antiemetics and antinauseants are used in various medical conditions and treatments, including:

Chemotherapy-induced nausea and vomiting
Postoperative nausea and vomiting
Motion sickness
Gastroenteritis

Mechanism of Action[edit | edit source]

Different classes of antiemetics work through various mechanisms to prevent nausea and vomiting:

Serotonin antagonists block the action of serotonin at 5-HT3 receptors in the central nervous system and gastrointestinal tract.
Dopamine antagonists block dopamine receptors in the brain, particularly in the chemoreceptor trigger zone.
Other antiemetics may work through different pathways, including neurokinin-1 receptor antagonists and antihistamines.

References[edit | edit source]

External Links[edit | edit source]

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