ATC code A04
ATC code A04 is a section of the Anatomical Therapeutic Chemical Classification System (ATC), a system used for the classification of drugs and other medical products. This section is specifically designated for antiemetics and antinauseants, which are medications used to prevent and treat nausea and vomiting.
Classification[edit | edit source]
The ATC code A04 is divided into several subgroups, each representing a different class of antiemetic and antinauseant medications. These subgroups include:
- A04A - Antiemetics and antinauseants
A04AA - Serotonin (5-HT3) antagonists[edit | edit source]
- A04AA01 - Ondansetron
- A04AA02 - Granisetron
- A04AA03 - Tropisetron
- A04AA04 - Dolasetron
- A04AA05 - Palonosetron
A04AB - Dopamine antagonists[edit | edit source]
- A04AB01 - Metoclopramide
- A04AB02 - Domperidone
- A04AB03 - Droperidol
A04AC - Other antiemetics[edit | edit source]
- A04AC01 - Aprepitant
- A04AC02 - Fosaprepitant
- A04AC03 - Netupitant
- A04AC04 - Rolapitant
Uses[edit | edit source]
Antiemetics and antinauseants are used in various medical conditions and treatments, including:
- Chemotherapy-induced nausea and vomiting
- Postoperative nausea and vomiting
- Motion sickness
- Gastroenteritis
Mechanism of Action[edit | edit source]
Different classes of antiemetics work through various mechanisms to prevent nausea and vomiting:
- Serotonin antagonists block the action of serotonin at 5-HT3 receptors in the central nervous system and gastrointestinal tract.
- Dopamine antagonists block dopamine receptors in the brain, particularly in the chemoreceptor trigger zone.
- Other antiemetics may work through different pathways, including neurokinin-1 receptor antagonists and antihistamines.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
| ATC codes |
|---|
| A Alimentary tract and metabolism |
| A01 Stomatological preparations |
| A02 Drugs for acid related disorders |
| A03 Drugs for functional gastrointestinal disorders |
| A04 Antiemetics and antinauseants |
| A05 Bile and liver therapy |
| A06 Drugs for constipation |
| A07 Antidiarrheals, intestinal anti-inflammatory/anti-infective agents |
| A08 Antiobesity preparations, excluding diet products |
| A09 Digestives, including enzymes |
| A10 Drugs used in diabetes |
| A11 Vitamins |
| A12 Mineral supplements |
| A13 Tonics |
| A14 Anabolic agents for systemic use |
| A15 Appetite stimulants |
| A16 Other alimentary tract and metabolism products |
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Contributors: Prab R. Tumpati, MD
