Anti-phospholipid antibody

Anti-phospholipid antibody (APA) is a type of autoantibody that targets phospholipids, a class of lipids that play a key role in cell membrane structure and function. APAs are associated with anti-phospholipid syndrome (APS), a disorder characterized by recurrent thrombosis and pregnancy complications.

Overview[edit | edit source]

APAs are a group of immunoglobulins that have the ability to bind to phospholipids. They are produced by the immune system and are typically found in individuals with autoimmune disorders such as systemic lupus erythematosus (SLE) and APS.

Anti-phospholipid Syndrome[edit | edit source]

APS is a disorder that can lead to both arterial and venous thrombosis as well as pregnancy-related complications such as miscarriage, stillbirth, and severe preeclampsia. The presence of APAs is a major diagnostic criterion for APS.

Diagnosis[edit | edit source]

The diagnosis of APA presence is typically made through blood tests. These tests look for the presence of APAs in the blood and their levels. High levels of APAs can indicate an increased risk of thrombosis or pregnancy complications.

Treatment[edit | edit source]

Treatment for individuals with APAs typically involves managing the symptoms and complications associated with APS. This can include the use of anticoagulant therapy to prevent thrombosis and close monitoring during pregnancy.