Autism Genetic Resource Exchange

Autism Genetic Resource Exchange (AGRE) is a research program and DNA repository dedicated to aiding and advancing knowledge about the genetics of autism. It was established in 1997 by Cure Autism Now, which later merged with Autism Speaks in 2007. The program collects, stores, and distributes DNA samples and clinical data from families with one or more members diagnosed with autism for use in research studies.

History[edit | edit source]

The Autism Genetic Resource Exchange was initiated by Cure Autism Now, a non-profit organization founded by parents of children with autism. The primary goal of AGRE was to expedite research into the genetic underpinnings of autism by providing researchers with access to a large, high-quality database of genetic material and associated clinical and demographic data. In 2007, Cure Autism Now merged with Autism Speaks, and AGRE became a program of Autism Speaks.

Collection and Distribution[edit | edit source]

AGRE collects DNA samples and clinical data from families affected by autism. The collected data includes detailed medical, developmental, and behavioral information. The DNA samples and data are then made available to qualified researchers worldwide. The goal is to facilitate and expedite research into the genetic causes of autism.

Impact[edit | edit source]

The Autism Genetic Resource Exchange has significantly contributed to the field of autism research. It has facilitated numerous studies that have led to the identification of several autism susceptibility genes. The availability of a large, well-characterized sample of genetic material and associated data has allowed researchers to make significant strides in understanding the genetic basis of autism.