Basaloid squamous cell lung carcinoma
| Basaloid squamous cell lung carcinoma | |
|---|---|
| ICD-10 | |
| ICD-9 | |
| DiseasesDB | |
| MedlinePlus | |
| eMedicine | |
| MeSH ID | |
Basaloid squamous cell lung carcinoma (BSCLC) is a rare and aggressive subtype of squamous cell carcinoma that occurs in the lung. It is characterized by its unique histological features and poor prognosis compared to other types of lung cancer.
Histopathology[edit | edit source]
Basaloid squamous cell lung carcinoma is distinguished by its basaloid appearance under the microscope. The tumor cells are small, with scant cytoplasm and hyperchromatic nuclei, arranged in nests or trabeculae. The stroma is often desmoplastic, and necrosis is common. These features differentiate it from other forms of lung cancer, such as adenocarcinoma and small cell lung carcinoma.
Epidemiology[edit | edit source]
BSCLC is a rare form of lung cancer, accounting for a small percentage of all lung cancer cases. It is more commonly diagnosed in older adults, particularly those with a history of smoking. The male-to-female ratio is approximately 3:1.
Clinical Presentation[edit | edit source]
Patients with basaloid squamous cell lung carcinoma often present with symptoms similar to other lung cancers, including persistent cough, chest pain, weight loss, and hemoptysis. Due to its aggressive nature, BSCLC may present at an advanced stage with metastasis to other organs.
Diagnosis[edit | edit source]
The diagnosis of BSCLC is confirmed through a combination of imaging studies, such as CT scan and PET scan, and histological examination of a biopsy sample. Immunohistochemical staining can help differentiate BSCLC from other types of lung cancer.
Treatment[edit | edit source]
Treatment options for basaloid squamous cell lung carcinoma include surgical resection, chemotherapy, and radiation therapy. The choice of treatment depends on the stage of the disease and the overall health of the patient. Due to its aggressive nature, the prognosis for BSCLC is generally poor, with a high likelihood of recurrence and metastasis.
Prognosis[edit | edit source]
The prognosis for patients with BSCLC is often poor, with a five-year survival rate significantly lower than other types of non-small cell lung carcinoma. Early detection and treatment are crucial for improving outcomes.
Research and Future Directions[edit | edit source]
Ongoing research is focused on understanding the molecular and genetic basis of basaloid squamous cell lung carcinoma, which may lead to the development of targeted therapies. Clinical trials are also exploring new treatment modalities to improve survival rates for patients with this aggressive cancer.
Also see[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
