Primary inoculation tuberculosis

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Primary inoculation tuberculosis
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Skin lesion, fever, lymphadenopathy
Complications	Tuberculous lymphadenitis, disseminated tuberculosis
Onset	Typically within 2-4 weeks after exposure
Duration	Variable, can be chronic
Types	N/A
Causes	Mycobacterium tuberculosis
Risks	Immunocompromised state, HIV infection, malnutrition
Diagnosis	Skin biopsy, tuberculin skin test, chest X-ray
Differential diagnosis	Cutaneous anthrax, sporotrichosis, cutaneous leishmaniasis
Prevention	BCG vaccine, avoiding exposure to infected individuals
Treatment	Antitubercular therapy (e.g., isoniazid, rifampicin, ethambutol, pyrazinamide)
Medication	N/A
Prognosis	Generally good with treatment
Frequency	Rare
Deaths	N/A

Primary inoculation tuberculosis (also known as primary cutaneous tuberculosis) is a form of tuberculosis that occurs at the site of inoculation. It is a rare form of tuberculosis, accounting for less than 1% of all cases.

Etiology

Primary inoculation tuberculosis is caused by the bacterium Mycobacterium tuberculosis. The bacteria enter the body through a break in the skin, such as a cut or scrape. This can occur through direct contact with a person who has active tuberculosis, or through contact with contaminated objects.

Symptoms

The symptoms of primary inoculation tuberculosis typically appear 2-4 weeks after exposure to the bacteria. The most common symptom is a painless skin lesion at the site of inoculation. Other symptoms may include fever, fatigue, weight loss, and swollen lymph nodes.

Diagnosis

Diagnosis of primary inoculation tuberculosis is often challenging due to its rarity and non-specific symptoms. It is typically confirmed through a combination of skin tests, blood tests, and imaging studies. A biopsy of the skin lesion may also be performed.

Treatment

Treatment for primary inoculation tuberculosis typically involves a combination of antibiotics, such as isoniazid, rifampin, pyrazinamide, and ethambutol. Treatment usually lasts for 6-9 months.

Prevention

Prevention of primary inoculation tuberculosis involves avoiding contact with individuals who have active tuberculosis, and practicing good hygiene to prevent the spread of the bacteria.

See also

• Tuberculosis
• Mycobacterium tuberculosis
• Cutaneous tuberculosis