Primary inoculation tuberculosis

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Primary Inoculation Tuberculosis

Chest X-ray showing primary tuberculosis

Primary inoculation tuberculosis (also known as primary cutaneous tuberculosis) is a form of tuberculosis that occurs at the site of inoculation. It is a rare form of tuberculosis, accounting for less than 1% of all cases.

Etiology[edit | edit source]

Primary inoculation tuberculosis is caused by the bacterium Mycobacterium tuberculosis. The bacteria enter the body through a break in the skin, such as a cut or scrape. This can occur through direct contact with a person who has active tuberculosis, or through contact with contaminated objects.

Symptoms[edit | edit source]

The symptoms of primary inoculation tuberculosis typically appear 2-4 weeks after exposure to the bacteria. The most common symptom is a painless skin lesion at the site of inoculation. Other symptoms may include fever, fatigue, weight loss, and swollen lymph nodes.

Diagnosis[edit | edit source]

Diagnosis of primary inoculation tuberculosis is often challenging due to its rarity and non-specific symptoms. It is typically confirmed through a combination of skin tests, blood tests, and imaging studies. A biopsy of the skin lesion may also be performed.

Treatment[edit | edit source]

Treatment for primary inoculation tuberculosis typically involves a combination of antibiotics, such as isoniazid, rifampin, pyrazinamide, and ethambutol. Treatment usually lasts for 6-9 months.

Prevention[edit | edit source]

Prevention of primary inoculation tuberculosis involves avoiding contact with individuals who have active tuberculosis, and practicing good hygiene to prevent the spread of the bacteria.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD