Hyperadrenocorticism

Hyperadrenocorticism (also known as Cushing's Syndrome) is a condition characterized by the overproduction of the hormone cortisol by the adrenal glands. This condition can be caused by various factors, including a tumor in the pituitary gland or the adrenal glands, or long-term use of corticosteroid medications.

Symptoms

The symptoms of hyperadrenocorticism can vary widely and may include:

• Weight gain
• Fatigue
• Muscle weakness
• High blood pressure
• High blood sugar
• Skin changes, such as bruising easily and purple stretch marks
• Osteoporosis
• Depression
• Anxiety

Causes

Hyperadrenocorticism can be caused by:

• A tumor in the pituitary gland (Pituitary-dependent hyperadrenocorticism)
• A tumor in the adrenal glands (Adrenal-dependent hyperadrenocorticism)
• Long-term use of corticosteroid medications

Diagnosis

The diagnosis of hyperadrenocorticism may involve:

• Medical history and physical examination
• Blood tests
• Urine tests
• Imaging tests, such as CT or MRI scans
• Dexamethasone suppression test

Treatment

The treatment for hyperadrenocorticism depends on the cause of the condition. It may include:

• Surgery to remove a tumor
• Radiation therapy
• Medications to control the production of cortisol
• Lifestyle changes, such as diet and exercise

See also

• Adrenal gland
• Cortisol
• Pituitary gland
• Cushing's Syndrome

Hyperadrenocorticism Resources
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