IUPHAR/BPS
IUPHAR/BPS Guide to Pharmacology
The IUPHAR/BPS Guide to Pharmacology is a comprehensive online resource that provides detailed information on drug targets and the substances that act on them. It is a collaborative project between the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS). The guide is designed to be a reliable and up-to-date source of information for researchers, educators, and students in the field of pharmacology.
Overview[edit | edit source]
The IUPHAR/BPS Guide to Pharmacology serves as a curated database that includes:
- Drug Targets: Information on receptors, enzymes, ion channels, and other proteins that are targets for drug action.
- Ligands: Details on small molecules, peptides, antibodies, and other substances that interact with drug targets.
- Pathways: Descriptions of biological pathways and processes that are influenced by pharmacological agents.
The guide is freely accessible and is continually updated by a team of expert curators and contributors from around the world.
History[edit | edit source]
The IUPHAR/BPS Guide to Pharmacology was launched in 2012 as a successor to the IUPHAR Database, which was originally developed to provide information on G protein-coupled receptors (GPCRs). The collaboration with the British Pharmacological Society expanded the scope of the database to include a wider range of drug targets and ligands.
Features[edit | edit source]
The guide includes several key features:
- Search Functionality: Users can search for specific drug targets, ligands, or pathways using a powerful search engine.
- Target Pages: Each target page provides detailed information on the structure, function, and pharmacology of the target, along with links to relevant literature.
- Ligand Pages: Each ligand page includes data on the chemical structure, biological activity, and therapeutic use of the ligand.
- Pathway Pages: Pathway pages offer insights into the role of drug targets and ligands in specific biological processes.
Educational Resources[edit | edit source]
The IUPHAR/BPS Guide to Pharmacology also offers educational resources, including:
- Tutorials: Guides on how to use the database effectively.
- Glossary: Definitions of key pharmacological terms.
- Teaching Materials: Resources for educators to use in teaching pharmacology.
Impact[edit | edit source]
The guide is widely used by researchers and educators in the field of pharmacology. It is cited in numerous scientific publications and serves as a reference for drug discovery and development.
Also see[edit | edit source]
External Links[edit | edit source]
- [IUPHAR/BPS Guide to Pharmacology Official Website](https://www.guidetopharmacology.org)
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Contributors: Prab R. Tumpati, MD
