Plasmodium malariae

Plasmodium malariae is a parasitic protozoa that causes malaria in humans. It is one of several species of Plasmodium parasites that infect humans including Plasmodium falciparum, Plasmodium vivax, and Plasmodium ovale.

Life Cycle

The life cycle of Plasmodium malariae involves two hosts. During a blood meal, a mosquito introduces the parasite into the human host. The parasite then travels to the liver where it matures and reproduces. The new parasites then infect red blood cells, where they continue to multiply, causing the symptoms of malaria.

Symptoms and Diagnosis

The symptoms of Plasmodium malariae infection include fever, chills, sweats, headaches, nausea and vomiting, body aches, and general malaise. Diagnosis is typically by microscopic examination of blood films or by antigen-based rapid diagnostic tests.

Treatment and Prevention

Treatment is typically with antimalarial drugs, including chloroquine and quinine. Prevention methods include the use of insecticide-treated nets, indoor residual spraying, and antimalarial drugs.

Epidemiology

Plasmodium malariae is found worldwide, but is particularly common in sub-Saharan Africa. It is less common than Plasmodium falciparum, but can cause severe illness and death, particularly in young children and pregnant women.

See Also

• Malaria
• Plasmodium
• Mosquito-borne disease