Polychromasia

From WikiMD's Food, Medicine & Wellness Encyclopedia

Polychromasia is a medical term that refers to the presence of large, immature, nucleated red blood cells (RBCs) in the blood. These cells are also known as reticulocytes. Polychromasia is often a sign of active RBC production in the bone marrow.

Causes[edit | edit source]

Polychromasia is usually a response to anemia, especially hemolytic anemia. It can also be seen in conditions such as thalassemia and sickle cell anemia. Other causes include blood loss, bone marrow disorders, and certain medications.

Diagnosis[edit | edit source]

Polychromasia is usually detected during a complete blood count (CBC) with a peripheral smear. The smear is examined under a microscope, and the presence of larger, bluish (polychromatic) RBCs indicates polychromasia.

Treatment[edit | edit source]

Treatment of polychromasia depends on the underlying cause. If it is due to anemia, treatment may include iron supplements, blood transfusions, or medications to increase red blood cell production. If it is due to a bone marrow disorder, treatment may include chemotherapy or a bone marrow transplant.

See also[edit | edit source]

Polychromasia Resources
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Contributors: Prab R. Tumpati, MD